diff --git a/rest_api/config.py b/rest_api/config.py
index 197917904..df8ea3e00 100644
--- a/rest_api/config.py
+++ b/rest_api/config.py
@@ -53,13 +53,20 @@ EMBEDDING_MODEL_FORMAT = os.getenv("EMBEDDING_MODEL_FORMAT", "farm")
 # File uploads
 FILE_UPLOAD_PATH = os.getenv("FILE_UPLOAD_PATH", "file-uploads")
 REMOVE_NUMERIC_TABLES = os.getenv("REMOVE_NUMERIC_TABLES", "True").lower() == "true"
-REMOVE_WHITESPACE = os.getenv("REMOVE_WHITESPACE", "True").lower() == "true"
-REMOVE_EMPTY_LINES = os.getenv("REMOVE_EMPTY_LINES", "True").lower() == "true"
-REMOVE_HEADER_FOOTER = os.getenv("REMOVE_HEADER_FOOTER", "True").lower() == "true"
 VALID_LANGUAGES = os.getenv("VALID_LANGUAGES", None)
 if VALID_LANGUAGES:
     VALID_LANGUAGES = ast.literal_eval(VALID_LANGUAGES)
 
+# Preprocessing
+REMOVE_WHITESPACE = os.getenv("REMOVE_WHITESPACE", "True").lower() == "true"
+REMOVE_EMPTY_LINES = os.getenv("REMOVE_EMPTY_LINES", "True").lower() == "true"
+REMOVE_HEADER_FOOTER = os.getenv("REMOVE_HEADER_FOOTER", "True").lower() == "true"
+SPLIT_BY = os.getenv("SPLIT_BY", "word")
+SPLIT_LENGTH = os.getenv("SPLIT_LENGTH", 1_000)
+SPLIT_OVERLAP = os.getenv("SPLIT_OVERLAP", None)
+SPLIT_RESPECT_SENTENCE_BOUNDARY = os.getenv("SPLIT_RESPECT_SENTENCE_BOUNDARY", True)
+
+
 # Monitoring
 LOG_LEVEL = os.getenv("LOG_LEVEL", "INFO")
 APM_SERVER = os.getenv("APM_SERVER", None)
diff --git a/rest_api/controller/file_upload.py b/rest_api/controller/file_upload.py
index 9fe781177..8051aed4a 100644
--- a/rest_api/controller/file_upload.py
+++ b/rest_api/controller/file_upload.py
@@ -12,10 +12,12 @@ from fastapi import UploadFile, File, Form
 from rest_api.config import DB_HOST, DB_PORT, DB_USER, DB_PW, DB_INDEX, DB_INDEX_FEEDBACK, ES_CONN_SCHEME, TEXT_FIELD_NAME, \
     SEARCH_FIELD_NAME, FILE_UPLOAD_PATH, EMBEDDING_DIM, EMBEDDING_FIELD_NAME, EXCLUDE_META_DATA_FIELDS, VALID_LANGUAGES, \
     FAQ_QUESTION_FIELD_NAME, REMOVE_NUMERIC_TABLES, REMOVE_WHITESPACE, REMOVE_EMPTY_LINES, REMOVE_HEADER_FOOTER, \
-    CREATE_INDEX, UPDATE_EXISTING_DOCUMENTS, VECTOR_SIMILARITY_METRIC
+    CREATE_INDEX, UPDATE_EXISTING_DOCUMENTS, VECTOR_SIMILARITY_METRIC, SPLIT_BY, SPLIT_LENGTH, SPLIT_OVERLAP, \
+    SPLIT_RESPECT_SENTENCE_BOUNDARY
 from haystack.document_store.elasticsearch import ElasticsearchDocumentStore
 from haystack.file_converter.pdf import PDFToTextConverter
 from haystack.file_converter.txt import TextConverter
+from haystack.preprocessor.preprocessor import PreProcessor
 
 
 logger = logging.getLogger(__name__)
@@ -30,7 +32,7 @@ document_store = ElasticsearchDocumentStore(
     index=DB_INDEX,
     label_index=DB_INDEX_FEEDBACK,
     scheme=ES_CONN_SCHEME,
-    ca_certs=False,
+    ca_certs=None,
     verify_certs=False,
     text_field=TEXT_FIELD_NAME,
     search_fields=SEARCH_FIELD_NAME,
@@ -54,6 +56,10 @@ def upload_file_to_document_store(
     remove_empty_lines: Optional[bool] = Form(REMOVE_EMPTY_LINES),
     remove_header_footer: Optional[bool] = Form(REMOVE_HEADER_FOOTER),
     valid_languages: Optional[List[str]] = Form(VALID_LANGUAGES),
+    split_by: Optional[str] = Form(SPLIT_BY),
+    split_length: Optional[int] = Form(SPLIT_LENGTH),
+    split_overlap: Optional[int] = Form(SPLIT_OVERLAP),
+    split_respect_sentence_boundary: Optional[bool] = Form(SPLIT_RESPECT_SENTENCE_BOUNDARY),
 ):
     try:
         file_path = Path(FILE_UPLOAD_PATH) / f"{uuid.uuid4().hex}_{file.filename}"
@@ -62,27 +68,31 @@ def upload_file_to_document_store(
 
         if file.filename.split(".")[-1].lower() == "pdf":
             pdf_converter = PDFToTextConverter(
-                remove_numeric_tables=remove_numeric_tables,
-                remove_whitespace=remove_whitespace,
-                remove_empty_lines=remove_empty_lines,
-                remove_header_footer=remove_header_footer,
-                valid_languages=valid_languages,
+                remove_numeric_tables=remove_numeric_tables, valid_languages=valid_languages
             )
             document = pdf_converter.convert(file_path)
         elif file.filename.split(".")[-1].lower() == "txt":
             txt_converter = TextConverter(
-                remove_numeric_tables=remove_numeric_tables,
-                remove_whitespace=remove_whitespace,
-                remove_empty_lines=remove_empty_lines,
-                remove_header_footer=remove_header_footer,
-                valid_languages=valid_languages,
+                remove_numeric_tables=remove_numeric_tables, valid_languages=valid_languages,
             )
             document = txt_converter.convert(file_path)
         else:
             raise HTTPException(status_code=415, detail=f"Only .pdf and .txt file formats are supported.")
 
-        document_to_write = {TEXT_FIELD_NAME: document["text"], "name": file.filename}
-        document_store.write_documents([document_to_write])
+        document = {TEXT_FIELD_NAME: document["text"], "name": file.filename}
+
+        preprocessor = PreProcessor(
+            clean_whitespace=remove_whitespace,
+            clean_header_footer=remove_header_footer,
+            clean_empty_lines=remove_empty_lines,
+            split_by=split_by,
+            split_length=split_length,
+            split_overlap=split_overlap,
+            split_respect_sentence_boundary=split_respect_sentence_boundary,
+        )
+
+        documents = preprocessor.process(document)
+        document_store.write_documents(documents)
         return "File upload was successful."
     finally:
         file.file.close()
diff --git a/test/test_rest_api.py b/test/test_rest_api.py
index 35f4433b0..0b63b3d5e 100644
--- a/test/test_rest_api.py
+++ b/test/test_rest_api.py
@@ -1,19 +1,20 @@
 import pytest
 from fastapi.testclient import TestClient
-
+from pathlib import Path
 from haystack import Finder
 from haystack.retriever.sparse import ElasticsearchRetriever
 
 # TODO: Add integration tests for other APIs
 
 
-def get_test_client_and_override_dependencies(reader, document_store_with_docs):
+def get_test_client_and_override_dependencies(reader, document_store):
     from rest_api.application import app
-    from rest_api.controller import search
+    from rest_api.controller import search, file_upload
 
-    search.document_store = document_store_with_docs
-    search.retriever = ElasticsearchRetriever(document_store=document_store_with_docs)
+    search.document_store = document_store
+    search.retriever = ElasticsearchRetriever(document_store=document_store)
     search.FINDERS = {1: Finder(reader=reader, retriever=search.retriever)}
+    file_upload.document_store = document_store
 
     return TestClient(app)
 
@@ -96,3 +97,14 @@ def test_query_api_filters(reader, document_store_with_docs):
     assert "New York" == response_json['hits']['hits'][0]["_source"]["answer"]
     assert "My name is Paul and I live in New York" == response_json['hits']['hits'][0]["_source"]["context"]
 
+
+@pytest.mark.slow
+@pytest.mark.elasticsearch
+@pytest.mark.parametrize("document_store", ["elasticsearch"], indirect=True)
+def test_file_upload(document_store):
+    assert document_store.get_document_count() == 0
+    client = get_test_client_and_override_dependencies(reader=None, document_store=document_store)
+    file_to_upload = {'file': Path("samples/pdf/sample_pdf_1.pdf").open('rb')}
+    response = client.post(url="/file-upload", files=file_to_upload)
+    assert 200 == response.status_code
+    assert document_store.get_document_count() > 0